Tirzepatide, which activates both GLP-1 and GIP receptors, may produce different effects compared to pure GLP-1 agonists
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Shapsis clinical experience, Ozempic works well for diabetic patients who also benefit from modest weight reduction but it is not optimized for aggressive weight loss
1, Table 2 and Supplementary Section 5) seems more likely, while any effect on psychotic, mood and anxiety disorders appears less consistent and in need of further investigation
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Agonists of the GLP-1 receptor have been shown to increase levels of markers of bone formation (osteocalcin and procollagen type 1 N-terminal propeptide [P1NP]) and protect against loss of bone mineral content in obese women after weight loss while having no effect on plasma CTX-1 concentrations [59, 60]