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Experimental Design and Methodology The study used both male and female 5xFAD transgenic mice, aged four months at the onset of testing

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Its less effective for hair loss caused by autoimmune conditions such as alopecia areata, scarring alopecia, or complete baldness, in which follicles are already gone

For this reason, synthetic analogs of neurosteroids, which are more resistant to metabolism and better able to cross the BBB, are under investigation for use as anxiolytics, antidepressants, cognitive enhancers, anesthetics, and anticonvulsants (132, 388, 389)

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