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at the first sign of rapid appetite return or rising weight trend

Kojic acid: This is a melanin inhibitor that is effective for hyperpigmentation

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This arrest is mediated by downregulation of enzymes and signaling molecules such as tyrosine cyclooxygenase, ornithine decarboxylase and multiple kinases, thus impeding neoplastic proliferation (60)

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The MHRA provides guidance on the use of unlicensed medicines in the UK, which clinicians and patients should consult if relevant