Both require provider oversight to ensure appropriate dosing, storage, and patient monitoring throughout treatment
Annual review should include symptom enquiry and consideration of associated autoimmune conditions, particularly thyroid disease, which may co-exist with pernicious anaemia
While results are promising, the treatment remains experimental
Dosing is incrementally increased over a 3 month period to decrease GI upset
The chronic disease model of obesity means, for many patients, that these are lifelong medications not short-term interventions
As an inherently important part of understanding the pharmacology of any drug involves discerning its cellular targets, we begin with an overview of the most important receptor populations and the organs where GLP-1R expression is questionable from a drug mechanism of action point of view