Research suggests combining beta-alanine with creatine may be advantageous when intake is sufficient (46 g daily) and sustained for at least 4 weeks (Trexler et al., 2015)
P = 0.06) ( The reported CV benefits were not associated with an increase in risk of severe hypoglycemia, retinopathy, or pancreatic adverse effects ( Moreover, a very recent multicenter, double-blind, randomized, placebo-controlled trial (the SELECT trial), showed that weekly 2.4 mg subcutaneous semaglutide was superior to placebo in reducing the risk of CV death, nonfatal MI, or nonfatal stroke at a mean follow-up of 39.8 months
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Staiger D, Stock JH
Summary: Increased urination with Saxenda is not a listed adverse effect but may occur due to weight loss, dietary changes, increased fluid intake, or improved glucose control