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While large human trials are pending, preclinical and mechanistic evidence is strong

Unlike earlier GH secretagogues, ipamorelin exhibits high selectivity, minimal activity at other hormonal axes (ACTH, cortisol, or prolactin), and potent GH release in both animals and humans

Gaetke LM, Chow CK

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Cytoprotective gastric pentadecapeptide BPC 157 resolves major vessel occlusion disturbances