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There is evidence that (R)-lipoic acid supplementation may be more potent than either the alpha-lipoic acid sold commercially or S-Lipoic acid

The support and personalization are unmatched

Historically, there was significant concern for notoriety bias (i.e., increased likelihood of case reporting when patients are exposed to a drug with a negative reputation), which was mitigated by studying disproportionality signals

While B12 supplementation addresses the deficiency, injection may be recommended by a healthcare provider as opposed to oral supplementation since malabsorption is often the cause

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If reactions are severe or don't resolve within hours, discontinue use and consult appropriate medical guidance