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[89] In pediatric patients with growth hormone deficiency, improvements in growth velocity may become apparent within the first few months of treatment, with more significant height gains typically observed after 6-12 months of consistent therapy

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The amount of food intake was monitored at HFD period (16 weeks) to assess consumption and changes in body weight from baseline to post-intervention (HFD) was calculated

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Nature 388 (6638), 121122

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