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In the 1 mg trial arm, liver fat fell 51% among participants with fatty liver, visceral fat fell 16%, and triglycerides declined. Ketones are a separate matter: the same substudy found -hydroxybutyrate rose only at 4 mg and above, so the 1 mg arm does not carry a ketone signal in that population. Modeled metabolic-health protocols place heavier, metabolically average profiles near 1 mg weekly

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[1] mhra.gov.uk or via the Yellow Card app)