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The one real argument for injecting is bypassing first-pass metabolism, and the strength of that argument depends entirely on which bioavailability study you believe (3.5% in mice versus 38.4% in rats)
Expert opinion on pharmacotherapy
doi: 10.1210/er.2018-00052 69 ZaidiMNewMBlairHZaloneA
However, researchers stress that observational studies alone cannot prove cause and effect
In people with fatty-liver disease (MASLD - metabolic dysfunction-associated steatotic liver disease), average liver fat fell by 82.4% at 24 weeks in the highest-dose group
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