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Noelting et al., 2022

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GROWTH FACTORS AND GROWTH FACTOR MODULATORS INCLUDING, BUT NOT LIMITED TO: Fibroblast growth factors (FGFs) Hepatocyte growth factor (HGF) Insulin-like growth factor 1 (IGF-1, mecasermin) and its analogues Mechano growth factors (MGFs) Platelet-derived growth factor (PDGF) Thymosin-4 and its derivatives e.g

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( Figure 1 ) It is also important to highlight the complex neuronal architecture of the tongue, as we should consider three different innervation types: 1) Autonomic innervation: generates the salivatory stimuli and regulation of local blood flow, that plays an important role in food pleasure and avoidance (26) 2) Motor innervation: control of muscle movement, such as mastication, swallow, speech, and breathing (27), and 3) Somatosensorial innervation: that encompasses taste perception, nociception and proprioception (18)