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The cardiovascular benefits of GLP-1RAs are well-established, with clinical trials demonstrating reductions in major adverse cardiovascular events (MACE), improved endothelial function, and lower blood pressure
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The most common adverse events were gastrointestinal and dose-related: diarrhea (27.4% / 33.5% / 33.6% at 4 / 9 / 12 mg vs 13.2% on placebo), nausea (13.7% / 20.8% / 28.0% vs 8.0%) and constipation (14.0% / 16.2% / 16.8% vs 9.4%)
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There could also be a risk of developing depression or suicidal thoughts in people who take this drug
The GLP-1 receptor agonist drugs you're referring to lower blood sugar in people with type 2 diabetes and powerfully reduce weight in people with obesity
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