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Metformin attenuated histopathological ocular deteriorations in a streptozotocin-induced hyperglycemic rat model
Moreover, GLP-1RAs can reverse EndMT induced by high glucose and IL-1 via activating the AMPK pathway, which was evidenced by augmenting an endothelium marker expression (CD31), as well as alleviating mesenchymal markers expression (SM22 (sensitive 22 kDa actin-binding protein of the calponin), vimentin and Snail) [119]
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Am J Trop Med Hyg 32: 10401048
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