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In TRIUMPH-1, participants receiving the highest dose achieved mean weight reductions approaching 28% at 80 weeks, with nearly half achieving at least 30% weight loss
Wegovys standard maintenance dose is 2.4mg, and the 7.2mg step-up dose (MHRA approved January 2026) produces 20.7% average weight loss
doi:10.1136/bmj.r1275 3.Gulcebi MI, Gavas S, Sisodiya SM
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They typically resolve or become manageable within 2-4 weeks at each new dose level
Instead, laboratory data must be interpreted within the broader clinical context including symptom patterns, exposure history, inflammatory markers, and overall regulatory stability
