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A recent longitudinal lipidomic study in American Indians demonstrated that changes in circulating lipids over time were significantly associated with changes in left ventricular mass index (80)
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If a 10 mg vial costs $X and standard dosing uses 2.5 mg per week (the entire vial in a month), microdosing at 1.0 mg per week stretches that same vial to over two months
Gastrointestinal side effects Digestive symptoms are the most common problem
However, they highlighted the limited evidence of similar effects in humans and called for longer-term trials to clarify the potential risks [134]
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