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In addition to the inherent challenges associated with these agents, Gln metabolism lacks tumor specificity and involves multiple metabolic pathways within cells, which can lead to false positives in areas of high metabolic activity
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5 How They Compare: Mechanism and Clinical Evidence Both NAC and glutathione ultimately support the same biological outcome -- higher intracellular glutathione and lower oxidative burden -- but they operate at different points in the pathway and carry different clinical evidence profiles
A., Oliveira, A
