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In addition to these neuronal groups, ARC also contains dopamine neurons which project to the anterior pituitary gland where they inhibit prolactin secretion (Figure 1)
Fortunately, even at large doses, vitamin B12 is generally considered safe, at least in the short term (more on that below)
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doi: 10.1146/annurev-nutr-071812-161148 45 SharmaAAnandSKSinghNDwivediUNKakkarP
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Nicotinamide adenine dinucleotide (NADH) and acetyl-CoA, two metabolic intermediates produced in the course of FAO, induce activation of PDK, which in turn phospho-inactivates the E1 subunit of the PDH complex, leading to lower rates of glucose oxidation and higher rates of lactate release 70
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