Both increase growth hormone naturally but through distinct biological mechanisms
The STEP trials for semaglutide 2.4 mg (Wegovy) showed: Average weight loss of approximately 15% of body weight over 68 weeks One-third of participants lost 20% or more of body weight Significant reductions in waist circumference, blood pressure, and cardiovascular risk markers The SURMOUNT trials for tirzepatide (Zepbound) showed even more impressive results: Average weight loss of 20-25% at the highest dose (15 mg) over 72 weeks More than half of participants lost 20% or more of body weight Significant improvements in type 2 diabetes markers, blood pressure, and lipid profiles The head-to-head comparison is clear
What are the side effects I should actually worry about
Gastroparesis (Stomach Paralysis) Gastroparesis, commonly referred to as stomach paralysis, is a medical condition in which the stomach muscles no longer move food through the digestive tract at a normal rate
The semaglutide dosage calculator can confirm the conversion for any concentration
They all function by making several chemical bonds with metal ions, thus rendering them much less chemically reactive