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Consistent with this pioneering study, Guan et al

In intact skin, the magnitude of this effect is lower and less certain because the barrier limits delivery

While moderate alcohol consumption might not cause severe problems in some people, its safest to avoid alcohol while taking Diflucan, especially if you have liver issues or consume alcohol regularly

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gradual dose tapering over several days is recommended

But for people with active cancer, a prior cancer diagnosis, or ongoing cancer treatment, NAC is something to discuss with an oncologist or healthcare provider before use