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Acknowledgements We thank the members of the Garcia-Bermudez laboratory for input
The diluent type and volume are specified by the product's SmPC
Pregnant or breastfeeding individuals should consult a doctor
Patients can usually resume regular activities immediately after the session, as the procedure requires minimal recovery
Two different selenium-dependent iodothyronine deiodinases (DIOs type 1 and 2) can deiodinate T 4 , thus increasing circulating T 3 , while a third iodothyronine deiodinase (DIO type 3) can convert both T 3 and T 4 to inactive metabolites ( Figure 3 ) (10, 11)
None of these routes are approved for clinical or therapeutic use in humans, and all remain experimental
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