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This medication, which contains a higher concentration of semaglutide, is prescribed for individuals with obesity or those who are overweight with at least one associated comorbidity, such as high blood pressure or type 2 diabetes
In 2024, Eli Lilly adopted a direct-to-consumer strategy for Zepbound, among other products, with its LillyDirect program
No clinical trial has directly compared once-weekly semaglutide to twice-weekly split dosing for side effect outcomes
Additional animal data show improvements in insulin sensitivity, reduction of hepatic fat (NASH models), and cardioprotective effects through improved lipid profiles
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FEBS J 282 , 17451767, (2015)
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