Long-term side effects: what the extended data shows The STEP trials ran for 68 weeks, and extension studies have provided data out to 2 years
(OK, OK, I really wanted to get svelte, fit my clothes again, and look better at parties but dodging diabetes was a close second.) Despite this wonder of preventive medicine materializing at our fingertips, under the Trump deal, an economic case can actually be made that it makes more fiscal sense for me to let my weight go unchecked, allow myself to develop diabetes, and then get my GLP-1 medicine fully covered by my insurance plan
it's about nutritional adequacy and optimization
Losing weight too quickly can lead to: Muscle loss : You may lose muscle along with fat, which can make it harder to keep the weight off
Route of administration and lifestyle fit For patients, the biggest differences lie in how these medications fit into their current lifestyle and life stage: Oral GLP1s require daily dosing Injectables are once weekly but require needles Roughly one in four adults has needle aversion, and oral options may open the door for patients previously unwilling or unable to use injectables
Foods high in fiber: Boost your health with fiber-rich foods. September 17, 2025