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In the late endosomes and lysosomes, accumulation of Mn 2+ may be obtained through the cation transporter ATP13A2 (PARK9), which has been identified as fundamental to prevent manganese toxicity, and proposed to shuttle manganese and other cations from the cytosol into the lysosomal lumen (Schmidt et al., 2009

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SS-31 (Elamipretide) SS-31 is a mitochondria-targeting peptide designed to support mitochondrial membrane integrity and energy production

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