PT-141 and PDE5 inhibitors work through completely different mechanisms and can be safely combined
Bydureon up to 30C for 4 weeks) For opened (in-use) GLP-1 pens: Multi-dose pens (Ozempic, Victoza, Saxenda, Byetta) have specific in-use storage requirements: Ozempic: Up to 6 weeks at temperatures up to 30C or refrigerated Victoza/Saxenda: Up to 1 month at temperatures up to 30C or refrigerated Byetta: Up to 30 days at temperatures up to 25C Write the date of first use on multi-dose pen labels Single-use pens (Wegovy, Trulicity) should be discarded after injection Bydureon must be used immediately after reconstitution Keep the pen cap on when not in use to protect from light Do not store with the needle attached, as this can cause air bubbles, leakage, or contamination Avoid exposure to direct sunlight or heat sources (e.g., radiators, car dashboards) If travelling, store in a cool bag with ice packs (ensure the pen does not come into direct contact with ice) General safety advice: Always inspect the medication before each injection (see next section) Dispose of used pens in a sharps container according to local NHS guidelines If you are unsure whether your pen has been stored correctly, do not use it seek advice from a healthcare professional Keep all medications out of the sight and reach of children Patients should familiarise themselves with the specific storage instructions for their prescribed GLP-1 product, as requirements vary significantly between brands
doi: 10.3402/mehd.v23i0.18573 332 Cruchet MuozSVerbeke PalmaSLera MarqusLEspinosa PizarroMNMalig MechasquiJSorensenK
When or if a GLP-1 RA is later introduced, your system will be better prepared to integrate it, with improved tolerance, fewer side effects, and longer-lasting results
Recent research also suggests semaglutide GLP-1 may have additional benefits, such as reducing the risk of major cardiovascular events in those with type 2 diabetes and high cardiovascular riska promising finding for many of our patients
Clinical Update 4/11/2023 PFAS in Drinking Water The EPA recently proposed federal limits on PFAS, chemicals with potentially negative health effects, in drinking water
