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There have been six publications to date that consider the results of the SELECT trial, none of which calculate a NNT, either for the primary or composite endpoints [21, 34,35,36,37,38]

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Oral semaglutide is typically taken on an empty stomach, ideally first thing in the morning, to support optimal absorption

For short-term use (days to weeks), refrigeration at 4C (39F) is acceptable

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Physiological Relevance: Its still debated whether GLP-3 has significant independent biological activity or if its primarily a byproduct of proglucagon processing