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An increased risk was also supported by results of a large meta-analysis comprising a total of 36 double-blind randomized clinical trials with DPP-4 inhibitors with a total of 54,664 patients: there was a 58% increased risk of acute pancreatitis with DPP-4 inhibitors compared with other therapies (127)

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doi: 10.3168/jds.2020-19974 2 RadzikowskiDMilczarekAJanochaAOstaszewskaUNiedziaekG