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P.MarcellinD.SaroA.et al (2021)
Abstract Introduction: Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are important regulators of metabolism and mediate the incretin effect
It is administered through intravenous (IV) or intramuscular (IM) injections
The muscle preservation evidence: what research actually shows No published clinical trial has specifically studied creatine supplementation in a semaglutide-treated population
In addition, given the inherent day-to-day variability in function in the frail target population as well as the presence of a host of concomitant conditions, the appropriate patient population to be studied remains to be defined, and demonstration of clinically meaningful efficacy may be difficult
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