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Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Set Variation Analysis (GSVA) analysis revealed significant activation of the glutathione metabolism pathway in drug-resistant breast cancer tissues compared to sensitive tissues after FEC (5-Fluorouracil, Epirubicin, and Cyclophosphamide) + docetaxel treatment (Fig
In most adults, prolonged sitting occupies a large portion of daily time, and this behavior has become more prevalent due to the coronavirus disease 2019 (COVID-19) pandemic, emerging as a novel determinant of CVD risk [11]
Here, using functional genetic screens, we identify uptake of lipoproteinsthe primary mechanism for lipid transport in circulationas a key determinant of ferroptosis sensitivity in cancer
Extracellular vesicles and exosomes in the control of the musculoskeletal health
The reaction between RT and GSH is based on a Michael addition reaction that is inherently reversible, has an appropriate dissociation equilibrium constant K d in the mM range and rapid reaction kinetics, and provides ratiometric readouts, thus allowing GSH quantification independent of the probe concentration
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