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This selectivity provides fat metabolism benefits with a more favorable side effect profile compared to systemic hormonal interventions

The compound then received GRAS (Generally Recognized as Safe) designation from the FDA for use as a food ingredient, which is a separate regulatory category from drug approval

Today, their impact on blood pressure is considered one of the key advantages of this drug class

It increases GLP-1 and another hormone called glucose-dependent insulinotropic polypeptide (GIP) This means it works in two ways while semaglutide only mimics GLP-1 hormones, tirzepatide also mimics GIP hormones

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Her patients already email asking to be upgraded to retatrutide after hearing about it on TikTok, even though she cannot prescribe it because it does not exist as an approved drug