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Previous studies have found that berberine inhibits cell death induced by 6-OHDA, and increases the expression of HO-1, ultimately protecting dopaminergic neurons (Kim et al., 2014)
From our hunter-gatherer days till relatively modern times, we went through cycles of feast and famine, and our bodies evolved to hold onto the calories we took in during times of plenty to sustain us through the times when food was scarce or nonexistent
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