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In general, if someone is struggling to meet their nutrition needs while on a GLP-1 inhibitor, stopping the prescription may be necessary

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Research Grant Support- Intercept, Galectin, BMS, Novo Nordisk, Viking, Pfizer

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However, emerging evidence suggests a potential link between GLP-1 therapy and altered pain perception, possibly through several mechanisms: 1- Neuroinflammation and Microglial Activation: GLP-1 receptors are expressed in the brainstem, spinal cord, and dorsal root ganglia, regions involved in pain modulation