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Combined triad-GSH metabolism model simulations: quinone metabolism and ROS production Following the parameterisation and sensitivity analysis, the triad model was expanded to include GS-H 2 Q adduct formation (quinone removal) and was combined with the glutathione metabolism model constructed by Reed et al
Glutathione is involved in various important liver detoxification processes, amino-acid transport, production of coenzymes, and the recycling of vitamins C and E
Argente J, Garca-Segura LM, Pozo J, Chowen JA
Epigenetic alterations have been suggested as a potential mechanism for metabolic phenotype switching in methionine restriction
cancer treatment or remission within the past five years requires explicit clearance and ongoing supervision from the clinician managing that history
BODIPY- C1-27A labelling of GSTO1 was decreased in C1-27 -treated tumours compared with the control group (Fig
