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As expected, the hydrodynamic size of NPs, determined by the DLS technique, is significantly higher in comparison with the one obtained by TEM or AFM
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The resultant change in the intracellular voltage in turn opens a voltage-gated calcium channel, allowing the influx of calcium, which directly causes the release of premade GH, stored in secretory granules
The 2-OH-E1 route catalyzed by CYP1A1 is a stable route, and it can be easily metabolized further through methylation, which is accomplished by catechol-O-methyltransferase (COMT)