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Including all doses in the charts above would have made them unreadable so we eliminated similar dose-responses

The healthy third leaf from apex was taken into account for recording leaf gaseous exchange attributes like transpiration rates (E) (mmol H 2 O m 2 s 1 ), stomatal conductance (gs) (mmol H 2 O m 2 s 1 ), photosynthetic rate (PN) (mol CO 2 m 2 s 1 ) and water use efficiency (WUE)

This clean math makes dose adjustments and microdosing protocols much simpler to implement

The convergence of enabling technologies, conceptual shifts toward polypharmacology, improved mechanistic tools, and evolving regulatory frameworks has fundamentally altered the translational calculus

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