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The most commonly reported adverse effects are gastrointestinal in nature and include: Nausea (particularly during dose escalation) Vomiting Diarrhoea Constipation Decreased appetite These effects are generally dose-dependent and tend to be most pronounced during the initial weeks of treatment when the dose is being gradually increased
doi: 10.1002/14651858.CD001018 241 MillerVMNaftolinFAsthanaSBlackDMBrintonEABudoffMJet al
& Gottlieb, R
Tirzepatide activates two receptors (GLP-1 and GIP)
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