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For HbA1c and fasting plasma glucose, each of the extended-release metformin regimens was at least as effective as immediate-release metformin

This is not correcting obesity, Stolte said

Hepatic Fat Accumulation: GLP-1 RAs were associated with reductions in hepatic steatosis, as reflected by decreases in intrahepatic fat accumulation (IHA) and liver fat content (LFC), both of which are measures of hepatic lipid deposition

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For the vast majority of patients, the immense, proven systemic benefits of GLP-1 medications, such as reversing severe obesity, stabilizing high blood sugar, reducing the risk of stroke, and preventing kidney failure, far outweigh this rare visual side effect