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10.1056/NEJMra1510062 62 WoottenD.ChristopoulosA.Marti-SolanoM.BabuM
Despite the wide presence of GLP-1R throughout bodily tissues, it is predominantly found in islet -cells and postprandial insulin release from these cells is dependent upon the ability of GLP-1 to interact with GLP-1R [27]
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They're telling patients to avoid eating heavy meals or eating close to bedtime (via The Atlantic)
Longacting glucagonlike peptide1 receptor agonists have direct access to and effects on proopiomelanocortin/cocaine and amphetaminestimulated transcript neurons in the mouse hypothalamus
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