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Some patients feel as though they want more frequent injections, and occasionally we test levels to see if they are receiving adequate replacement, but Im not sure how strong the evidence is to support this. GPs should consider periodic vitamin B12 testing of higher-risk patients who take metformin, even if they dont display symptoms of deficiency, the UK medicines regulator said earlier this year
The MHRA product information for hydroxocobalamin preparations lists several recognised side effects that patients should be aware of before commencing treatment
No guessing
This decrease is associated with the cessation of B12 injections at 6 weeks indicating injections may be effective only short-term
The 28-day rule comes from USP guidance and applies regardless of how much volume has been drawn
The absence of IGF-1 elevation carries important safety implications
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