References Sikiric P, Hahm KB, Blagaic AB, et al
Frontiers in Physiology, 14 , 1149120
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So we can excrete HUGE amounts of B12 in a short time if it is extraneous to the amount we currently need
Lack of robust human clinical trials prevents confirmation of consistent outcomes, optimal dosing, or long-term safety
In a study published in the Journal of Cutaneous and Aesthetic Surgery, the maximum dose used in one sitting was 5 g (6)