Bile becomes supersaturated with cholesterol, forming sludge or stones
The tradeoff is real
Theres also real-world evidence, which is taken from observational studies of people prescribed these medications in everyday clinical practice
Mold, Mycotoxins and a Dysregulated Immune System: A Combination of Concern
In the SURMOUNT-1 study, a phase 3 clinical trial in obese patients, randomized participants in a 1:1:1:1 ratio to tirzepatide (5, 10, 15 mg) or placebo over 72 weeks, significant weight reductions were observed at 72 weeks: 15.0% for 5 mg, 19.5% for 10 mg, 20.9% for 15 mg, compared to 3.1% for placebo [18]
Anales de Pediatra (English Edition)