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Numbered markings at 5, 10, 15, 20, 25, 30, 35, 40, 45, 50

After 48 hours, gentle warm compresses can help promote blood resorption

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According to UK guidance, metformin is contraindicated in patients with eGFR below 30 mL/min/1.73m, should not be initiated in those with eGFR 30-44 mL/min/1.73m, and requires dose review/reduction for eGFR 30-59 mL/min/1.73m

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Frago LM, Paeda C, Dickson SL, Hewson AK, Argente J, Chowen JA