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To reduce cancer treatment side-effects A few initial studies suggest possible benefit, but more studies are needed to determine safety and effectiveness

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Rizzo G, Disante M, Mencarelli A, et al

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Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for Vaccination-Induced antitumor immunity

For weight management, lack of at least 5% weight loss by 12 weeks at the maintenance dose warrants discussion about alternative strategies or dose optimization