Tirzepatide dosing follows its own escalation schedule: 2.5 mg for weeks 1 through 4, then 5 mg, 7.5 mg, 10 mg, 12.5 mg, and up to 15 mg at maintenance
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Similarly, if kidney function declines during treatmentwhether due to dehydration, illness, or age-related changesmetformin may need to be stopped because the kidneys cannot safely clear the medication
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