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In the pancreas, it enhances glucose-dependent insulin secretion whilst suppressing inappropriate glucagon release, thereby improving glycaemic control

During this time, the medication works to enhance the bodys ability to burn fat and decrease overall food intake

Mice were placed onto a cage hopper and infused with semaglutide, GLP-1MK-801 or vehicle (isotonic saline) over 60 s at a total infusion volume of 2 l through a Hamilton syringe mounted onto an automated syringe pump (Harvard Apparatus) and a 33-gauge internal cannula (PlasticsOne, C315IS-4/SPC, 2.5 mm)

[1] It is worth noting that weight loss itself, which commonly occurs with Ozempic treatment, can lead to changes in cardiovascular parameters and may contribute to the sensation of palpitations in some individuals

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