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FDA-approved GLP-1 receptor agonists come in short-acting and long-acting forms

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6 d) incresese osteoblastic differentiation and extracellular matrix production and mineralization [6]

The idea is that microdosing can: Reduce side effects: Its common to experience side effects when taking GLP-1s, especially gastrointestinal issues including nausea, vomiting, and diarrhea

approximately 89% for subcutaneous injection

35 When compared with the injectable GLP-1RA liraglutide 1.8 mg, oral semaglutide 14 mg was associated with an overall comparable incidence of GI AEs (Table 2 17,26-32,38 )