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however, when rigorously designed using proven analytic approaches to emulate reference trials, real-world evidence of several glucose-lowering drug classes have demonstrated strong concordance with trial estimates 20,22,32

For some, they observe slow, consistent progress

Education and safety are priorities

Additionally, optimizing blood pressure control, minimizing nephrotoxic medications, and implementing renoprotective measures, such as angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, are essential for preserving renal function and preventing disease progression in lupus patients with comorbid renal disease

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