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Patients are instructed to slowly wean off the dopamine medications over time (four to six weeks), says Dr

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This process, known as lipolysis, shrinks the fat cells and reduces the appearance of stubborn pockets of fat

In patients who develop unexplained lethargy, vomiting, or changes in mental status, hyperammonemic encephalopathy should be considered and an ammonia level should be measured [seeContraindications (4)andWarnings and Precautions (5.6, 5.9)]