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vi) the measurement data could not provide mean and standard deviation
As a result, in silico predictions are likely to yield some false positives (predicting immunogenicity where none exists) and false negatives (missing truly immunogenic peptides, which supports the FDA rationale for using orthogonal approaches)
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Research published in eBioMedicine confirmed that cagrilintide lowers body weight specifically through brain amylin receptors 1 and 3 (AMY1R and AMY3R), and these are distinct from the receptors that GLP-1 agonists activate
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