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Importantly, our results showed that artificial elevation of GSH levels significantly increase TMV resistance and suggested that GSH can restore wild type levels of TMV resistance in SA-deficient NahG plants
Tamai I, Nakanishi T, Kobayashi D, China K, Kosugi Y, Nezu J, et al
doi: 10.1038/nrg3173 204 CuiJChenYWangHYWangRF
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Ferroptosis is an iron-dependent regulated cell death due to accumulated lipid peroxidation and involved in physiological processes such as embryonic erythropoiesis and aging
This escalation should only occur if the lower dose is well-tolerated and additional benefit is needed to achieve treatment goals
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