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Moreover, weight-based daily insulin requirements (a marker of insulin sensitivity) were also reduced with semaglutide (0.77 (0.35) U kg day 1 ) compared to placebo (0.64 (0.28) U kg day 1 , P = 0.002)

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There are other medications, like tirzepatide and liraglutide, that work in similar ways, and some drugs use totally different methods to help people lose weight